Senigallia or Sinigaglia is a comune, episcopal see and port town on Italy's Adriatic coast, 25 km by rail north of Ancona, in the Marche, province of Ancona. The small port is formed by the lower reaches of the Misa, a stream which flows through the town between embankments constructed of Istrian marble.
Ravaged by Alaric, Senigallia was fortified by the Byzantines, and again laid waste by the Lombards in the 8th century and by the Saracens in the 9th.
It was the second easternmost of the five cities of the medieval Adriatic duchy of Pentapolis, east of Fano and west of Ancona.
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