Multiple sclerosis (abbreviated MS, also known as disseminated sclerosis) is a chronic, inflammatory disease that affects the central nervous system (CNS). MS can cause a variety of symptoms, including changes in sensation, visual problems, muscle weakness, depression, difficulties with coordination and speech, and pain. Although many patients lead full and rewarding lives, MS can cause impaired mobility and disability in the more severe cases.
Multiple sclerosis affects neurons, the cells of the brain and spinal cord that carry information, create thought and perception and allow the brain to control the body. Surrounding and protecting these neurons is a fatty layer known as the myelin sheath, which helps neurons carry electrical signals. MS causes gradual destruction of myelin (demyelination) and transection of neuron axons in patches throughout the brain and spinal cord, causing various symptoms depending upon which signals are interrupted. The name multiple sclerosis refers to the multiple scars (or scleroses) on the myelin sheaths. It is thought that MS results from attacks by an individual's immune system on the nervous system and is therefore categorized as an autoimmune disease.
Multiple sclerosis may take several different forms, with new symptoms occurring in discrete attacks or slowly accruing over time. Between attacks, symptoms may resolve completely, but permanent neurologic problems often persist. Although much is known about how MS causes damage, its exact cause remains unknown. MS currently does not have a cure, though several treatments are available which may slow the appearance of new symptoms. MS primarily affects adults, with an age of onset typically between 20 and 40 years, and is more common in women than in men.Dangond, F.Multiple sclerosis. eMedicine Neurology.Updated 2005 Apr 25. full text.Calabresi PA.Diagnosis and management of multiple sclerosis. Am Fam Physician. PMID 15571060full text.
More on [ Multiple sclerosis ]

Aberdeen Branch MS Society - Information, therapeutic and social resource.
Action MS Northern Ireland - Provides support and raises research funds.
Charity Action for Relief of Multiple Sclerosis (CHARMS) - Charity treatment center in Essex.
Get Motivated with Multiple Sclerosis - A self-help group based in Crawley, West Sussex. Information about membership and group objectives.
Mercia MS Therapy Centre - Coventry (U.K.) - Provides several alternative therapies and support to MS patients.
Meta Description: [ An independent Coventry charity, which provides therapies and support for MS sufferers and those close to them ]
MS First - Charity based at Bristol General Hospital performing research and assisting in the training of health professionals.
Meta Description: [ The Multiple Sclerosis Research Unit at Bristol General Hospital is dedicated to furthering Information, Research, Support and Training (FIRST). ]
MS Research Training and Education - Charity dedicated to extending knowledge about MS with the aim of providing better treatment.
Meta Description: [ UK charity dedicated to research into and information about Multiple Sclerosis (MS), with the aim of providing better treatment and hastening a cure. ]
Multiple Sclerosis National Therapy Centre - Self help group. Information regarding the disease and its treatment, fund-raising projects and lists of local contacts.
Multiple Sclerosis Resource Centre - Fact sheets, fundraising efforts and a bulletin board.
Meta Description: [ This is the home site of the Multiple Sclerosis Resource Centre, Multiple Sclerosis Resource Centre, MSRC, Telephone Counselling Service, 24hour, MS, Health, Disabled, Myelin, MRI, Physically Disabled, Service, MS Drugs, MS News, Beta Interferon, Disability, MS Research, Best Bet Diet, BBD, Discu... ]
Multiple Sclerosis Society - Support and advice to those living with and affected by multiple sclerosis. Extensive information available online.
Meta Description: [ UK Multiple Sclerosis Society - This is the home page to the Multiple Sclerosis Society site. Welcome. ]
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Multiple Sclerosis Society - Wirral Branch - Local, national and international MS news and links.
Meta Description: [ UK Multiple Sclerosis Society - ]
The Merlin Project - Registered charity working to build a Multiple Sclerosis Therapy Centre for Cornwall.
Meta Description: [ The Merlin Project: the fundraising arm of the Cornwall Multiple Sclerosis Therapy Center, UK registered charity number 1093691. Find out about our aims, how to help us and donate online using PayPal ]
The MS Trust - Charity providing information and education for people with multiple sclerosis and health professionals. Also includes research news.
Meta Description: [ Multiple Sclerosis Trust - UK charity providing information, education for people with multiple sclerosis and health professionals and funding research of direct relevance to people with MS ]
The Myelin Project - UK - Registered charity funding research for all demyelinating diseases (Multiple Sclerosis and the Leukodystrophies). Site offers details of research projects, patient information, reports of personal experiences and news items.
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The World of Multiple Sclerosis - Contains excellent information, people profiles, and reports on recent advances.
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