Genetics (from the Greek genno γεννώ= give birth) is the science of genes, heredity, and the variation of organisms. The word "genetics" was first suggested to describe the study of inheritance and the science of variation by the prominent British scientist William Bateson in a personal letter to Adam Sedgwick, dated April 18, 1905. Bateson first used the term "genetics" publicly at the Third International Conference on Genetics (London, England) in 1906.
Heredity and variations form the basis of genetics. Humans applied knowledge of genetics in prehistory with the domestication and breeding of plants and animals. In modern research, genetics provides important tools for the investigation of the function of a particular gene, e.g., analysis of genetic interactions. Within organisms, genetic information generally is carried in chromosomes, where it is represented in the chemical structure of particular DNA (deoxyribonucleic acid) molecules.
Genes encode the information necessary for synthesizing the amino-acid sequences in proteins, which in turn play a large role in determining the final phenotype, or physical appearance, of the organism. In diploid organisms, a dominant allele on one chromosome will mask the expression of a recessive gene on the other.
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Biostatistics Branch - Develops statistical methods and data resources to strengthen observational studies, intervention trials, and laboratory investigations of cancer.
Clinical Genetics Branch - Integrates clinical observations into an interdisciplinary approach involving clinical, genetic, epidemiologic, statistical and laboratory methods to define the role of susceptibility genes in cancer etiology.
Epidemiology and Biostatistics Program - Conducts independent and collaborative epidemiologic and biostatistical investigations to identify the distribution, characteristics, and causes of cancer in human populations.
Genetic Epidemiology Branch - Designs and conducts interdisciplinary clinical, epidemiologic, genetic, and laboratory studies of persons, families, and populations at high risk of cancer.
Human Genetics Program - Established in 1996 to provide an expanded focus for interdisciplinary research into the genetic determinants of human cancer.
Nutritional Epidemiology Branch - Conducts independent and collaborative research on the role of diet and nutritional status in cancer etiology.
Occupational and Environmental Epidemiology Branch - Conducts studies throughout the United States and around the world to identify and evaluate environmental and workplace exposures associated with the risk of cancer.
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Radiation Epidemiology Branch - Seeks to identify, quantify, and understand the risk of cancer in populations exposed to radiation, alone or in combination with other agents.
Viral Epidemiology Branch - Conducts multidisciplinary studies of carefully selected domestic and foreign populations, with the goal of clarifying the relationship of infectious agents, especially viruses, to human cancer and other diseases.